Designing a Long Acting Erythropoietin by Fusing Three Carboxyl-Terminal Peptides of Human Chorionic Gonadotropin Subunit to the N-Terminal and C-Terminal Coding Sequence
Figure 1
Construction of EPO-(CTP)3 chimeric gene. The chimeric gene contains the cDNA of human erythropoietin and three hCGβ carboxyl-terminal peptides that were ligated to the N-terminal (one) and to C-terminal (two) coding sequences.
