Research Article

Designing a Long Acting Erythropoietin by Fusing Three Carboxyl-Terminal Peptides of Human Chorionic Gonadotropin Subunit to the N-Terminal and C-Terminal Coding Sequence

Table 1

Comparative 3 week induction of haematocrit by EPO-(CTP)3 and rHuEPO.

Group numberMice/groupTreatmentRegimen: IV
Compound Dose μg/kg

1 Vehicle (control)0One dose per week
2rHuEPO15 μg/kg
3EPO-(CTP)315 μg/kg
4Commercial rHuEPO53 doses per week