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International Journal of Cell Biology
Volume 2012 (2012), Article ID 161837, 9 pages
TCA Cycle Defects and Cancer: When Metabolism Tunes Redox State
1Department of Biology, University of Rome “Tor Vergata”, Via della Ricerca Scientifica, 00133 Rome, Italy
2IRCCS San Raffaele Pisana, Via di Val Cannuta, 00166 Rome, Italy
Received 13 April 2012; Revised 1 June 2012; Accepted 15 June 2012
Academic Editor: Giuseppe Filomeni
Copyright © 2012 Simone Cardaci and Maria Rosa Ciriolo. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [15 citations]
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- P. J. Murphy, B. R. Cipriany, C. B. Wallin, C. Y. Ju, K. Szeto, J. A. Hagarman, J. J. Benitez, H. G. Craighead, and P. D. Soloway, “Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells,” Proceedings of the National Academy of Sciences, vol. 110, no. 19, pp. 7772–7777, 2013.
- James M. Phang, Wei Liu, and Chad Hancock, “Bridging epigenetics and metabolism Role of non-essential amino acids,” Epigenetics, vol. 8, no. 3, pp. 231–236, 2013.
- Amir Feizi, and Sergio Bordel, “Metabolic and protein interaction sub-networks controlling the proliferation rate of cancer cells and their impact on patient survival,” Scientific Reports, vol. 3, 2013.
- Angelo D’Alessandro, and Lello Zolla, “Proteomics and metabolomics in cancer drug development,” Expert Review of Proteomics, vol. 10, no. 5, pp. 473–488, 2013.
- Sewha Kim, Do Kim, Woo-Hee Jung, and Ja Koo, “Succinate dehydrogenase expression in breast cancer,” SpringerPlus, vol. 2, no. 1, pp. 299, 2013.
- Xiaohong Du, Shaogui Wan, Yibing Chen, Ping Qu, Xiaojun Huang, Xiaohe Yu, Hushan Yang, Yiguan Zhang, and Jinliang Xing, “Genetic Variants in Genes of Tricarboxylic Acid Cycle Key Enzymes Predict Postsurgical Overall Survival of Patients with Hepatocellular Carcinoma,” Annals of Surgical Oncology, 2014.
- William P. Katt, and Richard A. Cerione, “Glutaminase regulation in cancer cells: a druggable chain of events,” Drug Discovery Today, vol. 19, no. 4, pp. 450–457, 2014.
- Márcia Sá Monteiro, Márcia Carvalho, Maria de Lourdes Bastos, and Paula Guedes de Pinho, “Biomarkers in renal cell carcinoma: a metabolomics approach,” Metabolomics, 2014.
- Xu Guo, Deyang Li, Yousheng Wu, Yibing Chen, Xingchun Zhou, Xiaoyan Wang, Xiaojun Huang, Xiaofei Li, Hushan Yang, and Jinliang Xing, “Genetic variants in genes of tricarboxylic acid cycle key enzymes are associated with prognosis of patients with non-smallcell lung cancer,” Lung Cancer, 2014.
- Aleksandra Konieczna, Aneta Szczepańska, Karolina Sawiuk, Robert Łyżeń, and Grzegorz Węgrzyn, “Enzymes of the central carbon metabolism: Are they linkers between transcription, DNA replication, and carcinogenesis?,” Medical Hypotheses, 2014.
- Ludgero C. Tavares, Ivana Jarak, Fernando N. Nogueira, Paulo J. Oliveira, and Rui A. Carvalho, “Metabolic evaluations of cancer metabolism by NMR-based stable isotope tracer methodologies,” European Journal of Clinical Investigation, vol. 45, pp. 37–43, 2014.
- S. N. Ononye, W. Shi, V. B. Wali, B. Aktas, T. Jiang, C. Hatzis, and L. Pusztai, “Metabolic isoenzyme shifts in cancer as potential novel therapeutic targets,” Breast Cancer Research and Treatment, 2014.
- Huiqing Zhang, Xu Guo, Jingyao Dai, Yousheng Wu, Naijian Ge, Yefa Yang, Jiansong Ji, and Hongxin Zhang, “Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients,” Medical Oncology, vol. 31, no. 11, 2014.
- Kamiya Mehla, and Pankaj K. Singh, “MUC1: A Novel Metabolic Master Regulator,” Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2014.
- Kelvin L. Billingsley, Sonal Josan, Jae Mo Park, Sui Seng Tee, Eleanor Spielman-Sun, Ralph Hurd, Dirk Mayer, and Daniel Spielman, “ Hyperpolarized [1,4- 13 C]-diethylsuccinate: a potential DNP substrate for in vivo metabolic imaging ,” NMR in Biomedicine, 2014.