Plastin Family of Actin-Bundling Proteins: Its Functions in Leukocytes, Neurons, Intestines, and Cancer

Table 5

Studies on plastins in cancer cells.

Key words of the study	References
Ectopic expression of L-plastin in cancer
Transformed human fibroblasts	[11]
Many types of human cancer	[54]
L-plastin gene promoter in cancer	[55–57]
Ovarian steroid hormones	[58]
Prostate cancer and steroid hormone	[59]
Chromosome translocation	[60]
Breast cancer and expression pattern	[61]
Colorectal cancer and metastasis	[62]
Colon cancer, invasion, and loss of E-cadherin	[63]
Melanoma tumor invasion	[64]
T-plastin downregulation and CpG methylation	[65]
Ectopic expression of T-plastin in lymphoma
Cutaneous T cell lymphoma	[66, 67]
Sezary cells	[68, 69]
As a biomarker for cancer screening and diagnosis
Choroid plexus tumors and diagnostic marker	[71]
Bladder cancer and biomarker	[72]
Proteomics imaging and mass spectrometry	[73]
Colorectal cancer and human feces	[74]
Gene therapies targeting L-plastin gene
L-plastin promoter and gene therapy	[75–77]
Antisense L-plastin gene and tumor suppression	[78]