Review Article
Oxidative Stress-Induced Diseases via the ASK1 Signaling Pathway
Table 1
ASK1-related diseases and pathologies.
| Organ/tissue | Related diseases | Related pathologies | References |
| Nervous system | Alzheimer’s disease | Neuronal death | [13] | Parkinson’s disease | Neuronal death | [14] | Brain ischemia | Neuronal death | [15] | Multiple sclerosis | Inflammation | [16] |
| Liver | Hepatocarcinogenesis | Apoptosis | [17] |
| Heart | Hypertrophy, remodeling Cardiac injury | Cardiomyocyte apoptosis, interstitial fibrosis Capillary endothelial apoptosis | [18, 19] | [20] |
| Stomach | Gastric cancer | Cell proliferation | [21] |
| Skin | Skin tumorigenesis | Apoptosis, inflammation | [22] |
| Immune system | Infection | Septic shock | [6] |
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