Review Article

Pexophagy: The Selective Degradation of Peroxisomes

Figure 2

Comparison of peroxisome number and morphology in different eukaryotic cells and under different proliferation conditions. (a) Upper panel: Human HeLa cells expressing the peroxisomal marker, RFP-SKL, under basal growth conditions. Lower panel: S. cerevisiae cells expressing RFP-SKL after peroxisome induction in oleate medium. The relative number of peroxisomes per cell differs greatly between different eukaryotic cell types. Size marker = 2 μm. (b) Grayscale images of P. pastoris cells expressing BFP-SKL as peroxisomal marker. Upper panel: large, clustered methanol-induced peroxisomes; lower panel: small, unclustered oleate-induced peroxisomes. Note the difference in size and appearance of peroxisomes induced by different carbon sources. Size marker = 2 μm.
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