Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix

<table>In vitro three-dimensional human angiogenesis model for assaying cell invasion, migration, and sprout angiogenesis formation of human dermal microvascular endothelial cells (HDMEC) (a). Step I: HDMEC are cultured on the surface of microcarrier beads to generate EC-beads. Step II: EC-beads are embedded in fibrin gel, collagen gel, or fibrin/collagen gel, with or without the presence of angiogenesis factor. </table>

International Journal of Cell Biology

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Figure 1: Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix 

Figure 1 | Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix 