Natural Compounds as Regulators of the Cancer Cell Metabolism

Figure 2

Mitochondrial dysfunctions as pharmacological targets. Examples of natural compounds with a potential efficacy in cancer treatment. The figure schematizes their mechanism of action linked to mitochondrial dysfunctions. The compounds discussed herein have different mitochondrial targets, such as mitochondrial membrane potential (MMP), Bcl-2 family proteins (Bcl-2), reactive oxygen species (ROS), HIF-1α, mitochondrial metabolism (MM), and autophagy.