Quantifying Changes in the Cellular Thiol-Disulfide Status during Differentiation of B Cells into Antibody-Secreting Plasma Cells
Figure 3
Quantitative changes in protein thiol-disulfide redox state during B cell differentiation. Protein thiol-disulfide status was measured each day during B cell differentiation in three independent cultures induced with LPS, as illustrated in Figure 1. Values are given as mean ± SEM. The values for resting B cells are represented as “Day 0.” (a) The total fraction of protein cysteines per amino acid (total PS cal). (b) Percent of PSox relative to total PS cal. (c) Percent of PSSG relative to total PS cal. (d) PSSG as a percent of PSox.
