CXCL12 Modulates Prostate Cancer Cell Adhesion by Altering the Levels or Activities of β1-Containing Integrins

Figure 2

(a) DU145 cell spreading on COL-I, FN, 50K, and H/120 fragment of FN in the presence of various concentrations of CXCL12 (200 ng/mL). (b) Attachment of DU145 cells on FN and COL-I in the absence and presence of CXCL12 (200 ng/mL). (c) PC3 cell spreading on COL-I, FN, 50K, and H/120 fragment of FN in the presence of various concentrations of CXCL12 (200 ng/mL). (d) PC3 cell attachment on FN and COL-I in the absence and presence of CXCL12 (200 ng/mL). The level of nonspecific binding, determined from these cells attachment to wells coated with BSA alone, was subtracted. Values shown are mean ± standard deviation of triplicate wells.

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