CXCL12 Modulates Prostate Cancer Cell Adhesion by Altering the Levels or Activities of β1-Containing Integrins

Figure 3

CXCL12 induces focal adhesion disassembly, actin stress fiber rearrangement, and morphological change in DU145 cells seeded on FN. Cells were incubated for 2 hrs, fixed, and double-stained for vinculin and actin. Arrows in the images indicate localization of vinculin at the end of actin bundles in focal adhesion complexes.

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