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Parkinson’s Disease: Molecular Mechanisms, Diagnostics, and Therapies

Call for Papers

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that is characterized by the progressive loss of very specific type of neurons in the substantia nigra area (SNc), results in depletion of dopamine in the striatum. The vast majority of the PD cases are sporadic. However, several familial forms of PD associated genes have been identified which include Synuclein, Parkin, Pink1, DJ-1, and LRRK2. In addition to these genes, there are several other genes and regulatory elements that potentiate the risk of developing PD in certain individual.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular pathways underlying dopaminergic neurodegeneration in sporadic or familial type and the development of strategy to treat these conditions. We are also interested in articles describing the new model system that recapitulate the PD and their use in drugs screening. We also invite the article that covers early detection strategy and biomarker for PD and its future direction. Potential topics include, but are not limited to:

  • Recent developments of PD research familial and sporadic cases
  • Advances in genetics of PD
  • Latest technologies for clinical evaluation and measuring outcomes
  • Role of mitochondria in neurodegeneration
  • Gene delivery in PD research
  • Stem cells in PD therapy
  • Potential diagnostic approaches for detecting PD
  • Potential therapeutic modalities for prevention and treatment of PD

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijcb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/ijcb/parkin/ according to the following timetable:

Manuscript DueFriday, 13 June 2014
First Round of ReviewsFriday, 5 September 2014
Publication DateFriday, 31 October 2014

Lead Guest Editor

  • M. Emdadul Haque, Department of Biochemistry, College of Medicine and Health Sciences, UAE University, Al Ain, UAE

Guest Editors

  • Tohru Kitada, Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
  • Shreesh Ojha, Department of Pharmacology & Therapeutics, Animal Research Facility, College of Medicine & Health Sciences, UAE University, Al Ain, UAE
  • Francisco J. Díaz Corrales, Department of Cell Therapy and Regenerative Medicine, Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) Seville, Spain