Review Article
Identification and Quantification of Protein Glycosylation
Table 1
Lectins and their specific affinity to glycans.
| | Lectin | Origin | Specific affinity |
| | Mannose binding lectins |
| | Con A | Canavalia ensiformis | Branched α-mannosidic structures; high-mannose type, hybrid type and biantennary complex type N-glycans | | GNA | Galanthus nivalis | α-1–3 and α-1–6-linked high-mannose structures | | LCH | Lens culinaris | Fucosylated core region of bi- and triantennary complex type N-glycans |
| | Galactose/N-acetylgalactosamine binding lectins |
| | RCA | Ricinus communis | Galβ1-4GlcNAcβ1-R | | ECL | Erythrina cristagalli lectin | Galβ1-4GlcNAcβ1-R | | PNA | Arachis hypogaea | Galβ1-3GalNAcα1-Ser/Thr (T-Antigen) | | AIL | Artocarpus integrifolia | (Sia)Galβ1-3GalNAcα1-Ser/Thr (T-Antigen) | | VVL | Vicia villosa | GalNAcα-Ser/Thr (Tn-Antigen) |
| | Sialic acid/N-acetylglucosamine binding lectins |
| | WGA | Triticum vulgaris | GlcNAcβ1-4GlcNAcβ1-4GlcNAc, Neu5Ac (sialic acid) | | PHA | Phaseolus vulgaris | N-Acetylglucosamine | | SNA | Sambucus nigra | Neu5Acα2-6Gal(NAc)-R | | MAL | Maackia amurensis | Neu5Ac/Gcα2-3Galβ1-4GlcNAcβ1-R |
| | Fucose binding lectins |
| | UEA | Ulex europaeus | Fucα1-2Gal-R | | AAL | Aleuria aurantia | Fucα1-2Galβ1-4(Fucα1-3/4)Galβ1-4GlcNAc; R2-GlcNAcβ1-4(Fucα1-6)GlcNAc-R1 |
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