A Retrospective Analysis of Polymer Selection Using Solvent Casting: Formulation and DoE Optimization of the Amorphous Solid Dispersion of Amoxicillin Trihydrate by a Spray Drying Method

Table 1

Design batches with coded and decoded values.

Batch no.	Independent variables
	Coded value		Decoded value
	Feed rate (ml/min)	Feed concentration (gm/100 ml)	Feed rate (ml/min)	Feed concentration (gm/100 ml)
	−1	−1	3	3.75
	0	−1	4	3.75
	1	−1	5	3.75
	−1	0	3	5.625
	0	0	4	5.625
	1	0	5	5.625
	−1	1	3	7.5
	0	1	4	7.5
	1	1	5	7.5