Research Article

A Retrospective Analysis of Polymer Selection Using Solvent Casting: Formulation and DoE Optimization of the Amorphous Solid Dispersion of Amoxicillin Trihydrate by a Spray Drying Method

Table 3

Dissolution test of design batches.

Time (min)Percentage drug release (%)

1044.88 ± 1.2351.82 ± 0.9861.09 ± 2.5652.52 ± 1.8561.98 ± 1.9765.00 ± 0.6863.22 ± 2.8573.82 ± 2.1674.95 ± 1.66
2059.94 ± 1.5662.32 ± 2.7174.01 ± 1.6865.32 ± 1.4576.06 ± 0.6879.35 ± 1.0675.49 ± 2.7481.98 ± 0.8683.71 ± 1.52
3073.25 ± 2.1479.82 ± 1.8583.57 ± 1.3579.34 ± 2.0183.64 ± 1.3282.98 ± 1.8986.57 ± 1.7390.24 ± 1.8390.25 ± 2.11
6091.46 ± 1.6193.51 ± 2.5490.84 ± 1.9891.25 ± 0.9895.99 ± 2.2994.52 ± 2.1698.67 ± 2.8499.03 ± 2.61101.77 ± 1.26