A Retrospective Analysis of Polymer Selection Using Solvent Casting: Formulation and DoE Optimization of the Amorphous Solid Dispersion of Amoxicillin Trihydrate by a Spray Drying Method

Table 7

Constraints of optimization.

Constraints
Name	Goal	Lower limit	Upper limit
Feed rate (ml/min)	Maximize	−1	1
Feed concentration (gm/100 ml)	Maximize	−1	1
Percentage yield (%)	Maximize	30	33
Dissolution at 10 min (%)	Maximize	45	50
Angle of repose (°)	Minimize	30	35