Use of ICDAS-II, Fluorescence-Based Methods, and Radiography in Detection and Treatment Decision of Occlusal Caries Lesions: An In Vitro Study

Table 3

The area under the ROC curve (AUC), sensitivity (SE), and specificity (SP) for each method at the D₁ and D₃ diagnostic thresholds.

D1 diagnostic threshold	ICDAS-II	LF	FC		BW
AUC (95% CI)	1.0 (0.96–1.0)	0.88 (0.79–0.94)	0.95 (0.88–0.99)		0.56 (0.44–0.67)
SE (%)	100	69.0*	100**	82.1***	19.7
SP (%)	100	92.3*	7.7**	100***	92.3
D3 diagnostic threshold	ICDAS-II	LF	FC		BW
AUC (95% CI)	0.92 (0.84–0.97)	0.88 (0.79–0.94)	0.93 (0.85–0.98)		0.59 (0.48–0.67)
SE (%)	70.0	52.5*	19.44**	94.4***	27.5
SP (%)	95.5	90.9*	100**	77.3***	90.9

CI: confidence interval.
∗Cutoffs according to the literature [4].
∗∗Cutoffs according to the manufacturer’s recommendation.
∗∗∗Cutoffs according to the literature [5].