The Principal of Dynamic Contrast Enhanced MRI, the Method of Pharmacokinetic Analysis, and Its Application in the Head and Neck Region

Figure 6

A good tumor response to CRT, with an Ohboshi and Shimosato classification of III. The analyses were performed using a proprietary software program (PRIDE software, Philips Healthcare, Eindhoven, The Netherlands). Pre-CRT (a–c), Gd enhanced 𝑇₁ WI (a), 𝐾^trans map (b), 𝑣_𝑒 map (c), Post-CRT (d–f), Gd enhanced 𝑇₁ WI (d), 𝐾^trans map (e), 𝑣_𝑒 map (f). The tumor ROIs are delineated in red (a, d). 𝐾^trans increase from 0.14 to 0.22 and 𝑣_𝑒 decrease from 0.28 to 0.52.