A Comparative Evaluation of the Efficacy of Two Novel Desensitising Dentifrices

Table 2

Treatment group comparisons (ITT population) for Dentifrice A (Sensodyne Multi Action Iso-Active) versus Dentifrice B (Colgate Sensitive Pro-Relief). *From ANCOVA model with the following factors: treatment, baseline VAS stratification value (for Schiff and Tactile analyses), number of air sensitive teeth (covariate), and baseline (covariate). ^aCalculated as (adjusted mean difference/adjusted mean for Dentifrice B) × 100. ^bNegative values favour Dentifrice A; ^cpositive values favour Dentifrice A.

Time point	Sensitivity parameter	Difference^a (adjusted mean)*	% Difference^a	95% CI*		𝑃 value*
				Lower	Upper
Week 1	VAS^b	−1.7	25	−7.0	3.6	0.5263
	Schiff^b	0.0	−1	−0.2	0.2	0.9553
	Tactile^c	0.5	10	−3.0	3.9	0.7947
Week 2	VAS^b	−4.0	25	−10.6	2.5	0.2215
	Schiff^b	−0.1	7	−0.2	0.1	0.5453
	Tactile^c	−0.2	−3	−4.2	3.8	0.9232
Week 4	VAS^b	−3.8	18	−11.4	3.9	0.3310
	Schiff^b	−0.1	13	−0.3	0.1	0.1695
	Tactile^c	2.1	16	−3.0	7.3	0.4130
Week 8	VAS^b	−3.4	10	−11.7	4.9	0.4226
	Schiff^b	0.0	2	−0.2	0.2	0.7588
	Tactile^c	1.9	9	−3.2	7.0	0.4619