Clinical Outcome Following Oral Potentially Malignant Disorder Treatment: A 100 Patient Cohort Study

Table 3

Logistic regression models for “disease active” status.

Outcome	Risk factors	Univariate analysis		Multivariable analysis
		Odds (95% CI)	𝑃 value	Odds (95% CI)	𝑃 value
Disease active: recurrent or; further dysplasia,; malignant; transformation, and OSCC; development	Age	1.007 (0.976–1.040)	0.646
	Sex
	Females	Reference category
	Males	1.448 (0.806–3.455)	0.405
	Leukoplakia types
	Homogenous	Reference category
	Nonhomogenous	2.991 (1.160–7.713)	0.023	3.319 (0.799–13.779)	0.099
	PMDs site
	FOM	Reference category
	Tongue	3.381 (1.292–8.845)	0.013	3.323 (0.775–14.241)	0.106
	Other remaining sites	2.893 (0.971–8.620)	0.057	0.944 (0.171–5.218)	0.947
	Histopathology (WHO grading)
	Mid dysphasia	Reference category
	Moderate	1.129 (0.350–3.641)	0.839	1.960 (0.419–9.167)	0.393
	Severe	4.622 (1.527–13.990)	0.007	5.994 (1.282–28.018)	0.023
	CIS	4.800 (1.123–20.479)	0.034	17.104 (2.427–120.561)	0.004
	Binary grading
	Low grade	Reference category
	High grade	2.828 (1.182–6.678)	0.020
	Resection margin
	Free margins	Reference category
	Dysplastic margins	2.812 (1.073–7.371)	0.035	6.562 (1.545–27.878)	0.011
	PMDs size (mm^2)
	Minor < 200	Reference category
	Intermediate 200–600	2.327 (0.944–5.740)	0.067
	Major > 600	4.464 (1.035–18.394)	0.045