Conservative Treatment of Bisphosphonate-Related Osteonecrosis of the Jaw in Multiple Myeloma Patients

Table 2

Management of ONJ by stage.

Stage	𝑁	CHL rinses and observation plus removal of bony edges	Antibiotics plus removal of bony edges	Spontaneous apoptosis of sequestra	Minor surg. intervention-Sequstrectomy	Major surgical intervention
0	3	0	2 (67%)	0	1 (33%)	0
1	8	1 (12.5%)	1 (12.5%)	5 (62.5%)	1 (12.5%)	0
2	17	1 (5.9%)	4 (23.5%)	1 (5.9%)	11 (64.7%)	0
3	10	1 (10%)	3 (30%)	1 (10%)	3 (30%)	2 (20%)
Total	38	3 (7.9%)	10 (26.3%)	7 (18.4%)	16 (42.1%)	2 (5.3%)