Genetic Factors and the Risk of Periodontitis Development: Findings from a Systematic Review Composed of 13 Studies of Meta-Analysis with 71,531 Participants
Table 1
Main characteristics and results of the studies in meta-analysis published in the period from 2012 to 2016 and included in systematic search.
0.947 (0.814–1.103, P = 0.485) 1.112 (0.918–1.348, P = 0.278) 1.371 (0.810–2.320, P = 0.240) 0.940 (0.673–1.315, P = 0.719) 1.026 (0.806–1.305, P = 0.836) 2.138 (0.956–4.784, P = 0.064)
1.28 (1.07–1.54 P > 0.005) 2.01 (0.98–4.11, P > 0.005) 1.44 (1.25–1.66, P < 0.001) 1.54 (0.82–2.89, P = 0.175) 1.28 (1.07–1.54, P > 0.005) 2.01 (0.98–4.11, P > 0.005) 0.49 (0.31–0.77, P = 0.002) 0.93 (0.67–1.29, P = 0.656)
Med: inflammatory mediator, IL: interleukins, FGCGR: receptor Fcγ, COX-2: cyclooxygenase 2, MMP: matrix metalloproteinase, N: number of studies included in meta-analysis available, OR: Odds Ratio for the allelic evaluation (mutants allelic × wild allelic comparison), IC: confidence interval, pb: bases pair, and P < 0.05: statistic value significant.