Demineralized Freeze-Dried Bovine Cortical Bone: Its Potential for Guided Bone Regeneration Membrane

Figure 2

Distribution of inflammatory cells infiltration following subcutaneous implantation of BPCM and DFDBCBM at 2, 5, and 7 days after implantation. Mean of PMN count (a) in DFDBCBM group was significantly higher than BPCM at days 2 and 7, whereas mean of macrophage (b) and lymphocyte (c) count in DFDBCBM group was significantly higher than BPCM at day 2 after implantation. All inflammatory cells infiltration exhibited downward pattern from day 5 to day 7 indicating no prolonged inflammation. Microscopic picture of inflammatory cell infiltration at day 2 following subcutaneous implantation of BPCM (d) and DFDBCBM (e). PMN and lymphocyte were the predominant inflammatory cells seen in the tissue surrounding both membranes; blue arrow head pointing to PMN, green to lymphocytes, and yellow to respective membrane structure (H&E staining, ×1,000 magnification).

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