Genetic Association of MMP10, MMP14, and MMP16 with Dental Caries

Table 2

Genetic variants in MMPs 10, 14, and 16.

SNP	Chromosome	Position	MAF (COHRA1)	Base change	Location/functionality
MMP10
rs7948454	11	102641196	0.06	C-T	Downstream
rs12272341	11	102644601	0.13	A-G	Intronic
rs470154	11	102647310	0.06	C-G	Intronic
rs17293607	11	102650389	0.12	C-T	Missense Gly65Arg
rs559518	11	102656079	0.36	A-G	Intronic
MMP14
rs8003217	14	23304416	0.16	A-C	Downstream
rs762052	14	23308986	0.14	A-G	Intronic
rs10133740	14	23310131	0.15	C-T	Intronic
rs17243048	14	23311480	0.17	A-G	Intronic
rs12893368	14	23312208	0.17	C-G	Intronic
MMP16
rs17718917	8	89030490	0.08	A-G	Intergenic
rs1477907	8	89033615	0.09	A-G	Intergenic
rs16876790	8	89035664	0.38	A-T	Intergenic
rs2664368	8	89045674	0.20	C-T	Intergenic
rs10103111	8	89075226	0.23	C-T	Intronic
rs1824717	8	89075979	0.49	A-G	Intronic
rs17719876	8	89083319	0.08	C-T	Intronic
rs2616487	8	89084284	0.34	A-G	Intronic
rs6469206	8	89084691	0.45	G-T	Intronic
rs7826929	8	89084837	0.13	A-G	Intronic
rs2054415	8	89087358	0.05	G-T	Intronic
rs1551893	8	89102366	0.07	A-T	Intronic
rs1382104	8	89103325	0.44	C-T	Intronic
rs17720688	8	89104241	0.13	C-T	Intronic
rs10089111	8	89119305	0.38	G-T	Intronic
rs16878625	8	89125990	0.09	C-T	Intronic
rs10429371	8	89993488	0.22	C-T	Intergenic
rs2046315	8	90211100	0.13	A-G	Intergenic

Based on Build 37, MAF = minor allele frequency in the COHRA1 sample.