Salivary Fractalkine Differentiating Periodontitis from Periodontally Healthy Subjects

Table 5

Diagnostic accuracy of biomarkers among groups.

	Variable	AUC	p-Value	Optimal cutoff value	Sensitivity (%)	Specificity (%)
Control/stage I	CX3CL1	0.8	0.000	258.64	100	85.7
	CX3CR1	0.938	0.000	0.739	100	92.9
Control/stage II	CX3CL1	0.583	0.287	370.297	60.7	46.4
	CX3CR1	0.482	0.819	2.879	46.4	53.6
Control/stage III	CX3CL1	1	0.000	192.695	100	96.4
	CX3CR1	1	0.000	0.627	100	96.4
Control/periodontitis	CX3CL1	0.794	0.000	390.18	78.2	42.9
	CX3CR1	0.796	0.000	2.879	78.2	53.6

CX3CL1: Fractalkine ligand; CX3CR1: Fractalkine receptors; AUC: area under the curve.