Comparison of the Pharmacological Effects of Paricalcitol and Doxercalciferol on the Factors Involved in Mineral Homeostasis
Figure 5
Effect of paricalcitol and active doxercalciferol on the expression of PTH, VDR, and CaSR mRNA in pig parathyroid cells. Cells were treated with paricalcitol and active doxercalciferol at indicated concentrations (in log ) for 24 hours. Samples were processed and real-time RT-PCR performed. The mRNA expression level was normalized to the GAPDH mRNA level. C: control (no drug treatment); doxer: doxercalciferol. Values shown are mean the standard deviation ( = 4). One way ANOVA Dunnett test with 95% confidence intervals of difference was performed for statistical comparisons. , , versus Control (C, no drug treatment). versus Control (C).
