Impact of Sleep and Its Disturbances on Hypothalamo-Pituitary-Adrenal Axis Activity

Figure 4

Effect of an 8-hour sleep advance on cortisol profiles. Mean (+ SEM) cortisol profiles obtained during 68 consecutive hours including baseline conditions and 2 postshift periods, that is, after an 8-hour advance of the sleep-wake and dark-light cycles. Black bars represent the sleep periods whereas wake time was spent in dim light conditions. (Adapted from Caufriez et al. [68].)