Effect of Glucose or Fat Challenge on Aspirin Resistance in Diabetes

Table 3

Response to glucose ingestion.

	11-dh-TxB2 (pg/mg of creatinine)		VN (ARU)
	Nonresponders (𝑛=13)	Responders (𝑛=19)	Nonresponders (𝑛=14)	Responders (𝑛=10)
Pre-Glucose  % of ASA-R	942 ± 117	1693 ± 364^†	430.4±18.5	457.6±22.3
	15	55	7	10
Post-Glucose  % ASA-R	954.1 ± 122	2799 ± 513^†‡	428.5 ± 18.1	527.1 ± 25.8^‡
	15	63	7	33
CVD (𝑛)	1	4^†	0	4^†
Duration of diabetes	6.3 ± 1.7	8.4 ± 1.7	4.9 ± 1.4	11.1 ± 2.3^†
LDL (mg/dL)	102 ± 8.6	126 ± 8.3^†	105 ± 9.4	121 ± 11.6

Responders were defined by more than 10% increase in ASA-R measures after glucose ingestion. ASA-R: aspirin resistant, ASA-S: aspirin sensitive, CVD: cardiovascular disease.
Data are presented as means ± SE. The following group comparisons denote 𝑃<.05.  ^†Non-responders: Responders, ^‡Pre: Post.