Clinical Study
Procoagulant and Anticoagulant Factors in Childhood Hypothyroidism
Table 3
Data on baseline coagulation tests, pro-coagulant and anti-coagulant proteins in the patients and controls.
| | Variables | Patients () | Controls () | |
| | PT (sc) | 11.1 (1.22) | 11.1 (1.00) | 0.643* | | aPTT (sc) | 34.9 ± 4.98 | 35.9 ± 5.12 | 0.321† | | INR (ratio) | 1.0 (0.11) | 1.0 (0.09) | 0.662* | | Fibrinogen (mg/dL) | 244.1 ± 81.35 | 292.5 ± 81.02 | 0.039† | | TT (sc) | 19.4 (3.20) | 14.1 (2.60) | 0.029* | | FII (%) | 102.7 (30.25) | 114.5 (23.60) | 0.123* | | FV (%) | 114.6 ± 31.60 | 123.8 ± 22.07 | 0.080† | | FVII (%) | 84.0 ± 20.83 | 84.1 ± 17.99 | 0.983† | | FVIII (%) | 82.2 (43.50) | 91.5 (38.00) | 0.028* | | FIX (%) | 95.6 ± 29.28 | 94.5 ± 31.86 | 0.860† | | FX (%) | 100.7 ± 25.87 | 109.9 ± 25.04 | 0.063† | | FXII (%) | 121.2 ± 30.13 | 122.2 ± 34.84 | 0.875† | | FXII (%) | 131.5 ± 27.70 | 120.3 ± 35.87 | 0.072† | | AP (%) | 119.6 ± 18.42 | 124.1 ± 14.02 | 0.155† | | vWF (%) | 105.1 (66.35) | 93.4 (61.80) | 0.025* | | AT (%) | 98.5 ± 28.22 | 115.3 ± 26.38 | 0.002† | | PC (%) | 81.5 (52.75) | 92.0 (58.00) | 0.022* | | PS (%) | 73.4 ± 24.63 | 83.2 ± 20.10 | 0.026† | | fPS (%) | 84.1 ± 18.10 | 100.9 ± 20.31 | <0.001† | | PL (%) | 91.0 (44.00) | 99.0 (37.00) | 0.184* | | APCR (R) | 3.0 (0.40) | 2.9 (0.40) | 0.127* | | LA (R) | 1.0 (0.18) | 1.1 (0.17) | 0.189* |
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AP: antiplasmin; AT: antithrombin; F: factor; fPS: free protein S; PC: protein C; PL: plasminogen; PS: protein S; PT: prothrombin time; aPTT: activated partial thromboplastin time; TT: thrombin time; vWF: von Willebrand’s factor. *Mann Whitney U, †Student’s t-test.
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