Clinical Study
Application of the New Classification on Patients with a Disorder of Sex Development in Indonesia
Table 3
Additional clinical data in patients with known histology results.
| Number | Age | Gender | Karyotype | Quigley stage | Hormonal analysis | Imaging | Surgery | Mutation | Histology | Diagnosis |
| 1 | 33 | Female | 46 XY | 4 | Very high testosterone with slightly increased values of gonadotropins | No abnormalities | Laparoscopy | No | Ovarian Leydig cell tumor lacking histological signs of malignancy | Disorder of androgen excess |
| 2 | 23 | Female | 46 XY | 6 | High basal testosterone level | No abnormalities | Gonadectomy | AR neg | Leydic cell hyperplasia and atrophy of most seminiferous tubules but no evidence of CIS | Disorder of androgen action |
| 3 | 13 | Male | 46 XY | 3 | High basal testosterone level | Gonads not in situ* no uterus and adnexa 1/3 vagina present | Laparoscopy gonadectomy | AR neg | CIS | PAIS |
| 4 | 3 | Male | 46 XX/XY | 2 | hCG test: good response testosterone | No abnormalities | Gonadectomy | SRY neg | Ovarian tissue with multiple cysts including primordial follicles and granulosa cells | Gonadal dysgenesis |
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*Gonads already removed before ultrasound.
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