Morphological and Histopathological Changes in Orofacial Structures of Experimentally Developed Acromegaly-Like Rats: An Overview

Figure 3

(a, b) Coronal sections of the dorsal superior longitudinal tongue muscle from an IGF-I-treated rat (a) and a control rat (b) at 14 weeks of age (hematoxylin-eosin staining, 100x magnification, bars = 100 μm). (c–e) Muscle bundle width (c), ratio of the muscle parts (d), and total epithelial thickness (e). In (c–e), data represent the mean ± SD of six rats (*𝑃<0.05, **𝑃<0.01, ***𝑃<0.001 versus control); adapted from a previous report [8].

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