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International Journal of Endocrinology
Volume 2012 (2012), Article ID 381824, 15 pages
http://dx.doi.org/10.1155/2012/381824
Research Article

A Cell Model for Conditional Profiling of Androgen-Receptor-Interacting Proteins

Department of Paediatrics, Addenbrooke’s Hospital, University of Cambridge, Level 8, Box 116, Hills Road, Cambridge CB2 0QQ, UK

Received 7 September 2011; Revised 2 November 2011; Accepted 7 November 2011

Academic Editor: Olaf Hiort

Copyright © 2012 K. A. Mooslehner et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Jaaskelainen, A. Deeb, J. W. Schwabe, N. P. Mongan, H. Martin, and I. A. Hughes, “Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains,” Journal of Molecular Endocrinology, vol. 36, no. 2, pp. 361–368, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. I. A. Hughes, B. A. J. Evans, R. Ismail, and J. Matthews, “Complete androgen insensitivity syndrome characterized by increased concentration of a normal androgen receptor in genital skin fibroblasts,” Journal of Clinical Endocrinology and Metabolism, vol. 63, no. 2, pp. 309–315, 1986. View at Scopus
  3. S. Kerkhofs, S. Denayer, A. Haelens, and F. Claessens, “Androgen receptor knockout and knock-in mouse models,” Journal of Molecular Endocrinology, vol. 42, no. 1, pp. 11–17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Araki, K. Suzuki, R. J. Matusik, M. Obinata, and M. C. Orgebin-Crist, “Immortalized epididymal cell lines from transgenic mice overexpressing temperature-sensitive simian virus 40 large T-antigen gene,” Journal of Andrology, vol. 23, no. 6, pp. 854–869, 2002. View at Scopus
  5. A. Umar, T. M. Luider, C. A. Berrevoets, J. A. Grootegoed, and A. O. Brinkmann, “Proteomic analysis of androgen-regulated protein expression in a mouse fetal vas deferens cell line,” Endocrinology, vol. 144, no. 4, pp. 1147–1154, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. D. W. Huang, B. T. Sherman, and R. A. Lempicki, “Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources,” Nature Protocols, vol. 4, no. 1, pp. 44–57, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. D. W. Huang, B. T. Sherman, and R. A. Lempicki, “Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists,” Nucleic Acids Research, vol. 37, no. 1, pp. 1–13, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. J. Reimand, M. Kull, H. Peterson, J. Hansen, and J. Vilo, “g:Profiler—a web-based toolset for functional profiling of gene lists from large-scale experiments,” Nucleic Acids Research, vol. 35, pp. W193–W200, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. E. Fernández, M. O. Collins, R. T. Uren et al., “Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins,” Molecular Systems Biology, vol. 5, article 269, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Seenundun and B. Robaire, “Time-dependent rescue of gene expression by androgens in the mouse proximal caput epididymidis-1 cell line after androgen withdrawal,” Endocrinology, vol. 148, no. 1, pp. 173–188, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Yanai, M. Suzuki, and M. Obinata, “Hepatocyte cell lines established from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene,” Experimental Cell Research, vol. 197, no. 1, pp. 50–56, 1991. View at Publisher · View at Google Scholar · View at Scopus
  12. E. Saade, U. Mechold, A. Kulyyassov, D. Vertut, M. Lipinski, and V. Ogryzko, “Analysis of interaction partners of H4 histone by a new proteomics approach,” Proteomics, vol. 9, no. 21, pp. 4934–4943, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Nishimura, H. J. Ting, Y. Harada et al., “Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator,” Cancer Research, vol. 63, no. 16, pp. 4888–4894, 2003. View at Scopus
  14. R. Jasalava, H. Martinez, J. Thumar et al., “Identification of putative androgen receptor interaction protein modules: cytoskeleton and endosomes modulate androgen receptor signaling in prostate cancer cells,” Molecular and Cellular Proteomics, vol. 6, no. 2, pp. 252–271, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. G. Pottiez, N. Haverland, and P. Ciborowski, “Mass spectrometric characterization of gelsolin isoforms,” Rapid Communications in Mass Spectrometry, vol. 24, no. 17, pp. 2620–2624, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. B. Lemon, C. Inouye, D. S. King, and R. Tjian, “Selectivity of chromatin-remodelling cofactors for ligand-activated transcription,” Nature, vol. 414, no. 6866, pp. 924–928, 2001. View at Publisher · View at Google Scholar · View at Scopus
  17. K. W. Trotter and T. K. Archer, “Reconstitution of glucocorticoid receptor-dependent transcription in vivo,” Molecular and Cellular Biology, vol. 24, no. 8, pp. 3347–3358, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. K. Cui, P. Tailor, H. Liu, X. Chen, K. Ozato, and K. Zhao, “The chromatin-remodeling BAF complex mediates cellular antiviral activities by promoter priming,” Molecular and Cellular Biology, vol. 24, no. 10, pp. 4476–4486, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Lessard, J. I. Wu, J. A. Ranish et al., “An essential switch in subunit composition of a chromatin remodeling complex during neural development,” Neuron, vol. 55, no. 2, pp. 201–215, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. H. J. Ting, B. Y. Bao, C. L. Hsu, and Y. F. Lee, “Androgen-receptor coregulators mediate the suppressive effect of androgen signals on vitamin D receptor activity,” Endocrine, vol. 26, no. 1, pp. 1–9, 2005. View at Scopus
  21. B. Mooso, A. Madhav, S. Johnson et al., “Androgen receptor regulation of vitamin D receptor in response of castration-resistant prostate cancer cells to 1α-hydroxyvitamin D5: a calcitriol analog,” Genes and Cancer, vol. 1, no. 9, pp. 927–940, 2010. View at Publisher · View at Google Scholar
  22. K. K. Mak, M. H. Chen, T. F. Day, P. T. Chuang, and Y. Yang, “Wnt/β-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation,” Development, vol. 133, no. 18, pp. 3695–3707, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. G. Lagger, D. O'Carroll, M. Rembold et al., “Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression,” The EMBO Journal, vol. 21, no. 11, pp. 2672–2681, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. L. H. Kasper, F. Boussouar, P. A. Ney et al., “A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis,” Nature, vol. 419, no. 6908, pp. 738–743, 2002. View at Publisher · View at Google Scholar · View at Scopus