Review Article
Surgery and Radiosurgery for Acromegaly: A Review of Indications, Operative Techniques, Outcomes, and Complications
Table 2
Radiosurgery case series including greater than 50 acromegalic patients.
| | Number of Patients | Type of radiosurgery | Mean marginal dose (Gy) | Acromegaly remission (%) | Mean followup (months) | Pituitary hormone deficiency (%) |
| Losa et al. 2008 [30] | 83 | GK | 25 (goal) | 60.2 | 69 | 8.5 | Jagannathan et al. 2008 [26] | 95 | GK | 22 | 53 | 57 | 34 | Vik-Mo et al. 2007 [31] | 61 | GK | 26.5 | 17 | 66 | 13 | Voges et al.2006 [32] | 64 | LINAC | 15.3* | 37.5 | 81.9* | 12.3* | Jezkova 2006 [33] | 96 | GK | 32 | 44 | 53.7 | 27 | Castinetti et al. 2005 [34] | 82 | GK | 26.3 | 17 | 49.5 | 17 | Kobayashi et al. 2005 [35] | 67 | GK | 18.9 | 16.7 | 63.3 | 14.6 | Jane et al. 2003 [36] | 64 | GK | 15* | 36 | NR | 28 | Zhang et al. 2000 [37] | 68 | GK | 31.3 | 96 | >24 | NR |
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*represents all adenomas in study not specific to growth hormone pituitary adenomas. NR = value not recorded in study.
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