Preventive Treatment with Methylprednisolone Paradoxically Exacerbates Experimental Autoimmune Encephalomyelitis

Figure 2

Immunohistochemical analysis of EAE following preventive GC administration. Immunohistochemical stainings are depicted for infiltrating T cells (left), macrophages/monocytes (middle), and albumin as marker of blood-brain-barrier integrity (right) in the lumbar spinal cord of one representative mouse of each treatment group (top: 100 mg/kg MP, middle: control, bottom: 100 mg/kg Dex) sacrificed on day 12. Magnification = 200x.

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