Table 2:
The effects of dihydropyridine CCBs on angiotensin II-induced expression of steroidogenic enzymes.
Dihydropyridine CCB
Type of affecting Ca
2+
channels
StAR
CYP11B1
CYP11B2
Amlodipine
L, T
→
Azelnidipine
L, T
↓
↓
↓
Benidipine
L, T
↓
↓
Cilnidipine
L, N
→
↓
Efonidipine
L, T
↑
↓
↓
Nifedipine
L
→
↓
↓
Nitrendipine
L
→
→