Role of Adipokines and Other Inflammatory Mediators in Gestational Diabetes Mellitus and Previous Gestational Diabetes Mellitus

Table 1

Adipokines and other inflammatory mediators in normal pregnancy, obesity/DM, GDM, and pGDM.

	Pregnancy	Obesity/DM	GDM	pGDM
Adiponectin [43, 50–92]	Decreased Unaltered	Decreased	Decreased	Decreased
Leptin [43, 91–105]	Increased	Increased	Increased Unaltered Decreased	Increased Unaltered
Resistin [68, 70, 73, 76, 106–121]	Increased	Increased	Increased Unaltered Decreased	Increased
RBP-4 [106, 122–138]	Increased Decreased	Increased Decreased	Increased Decreased Unaltered	Increased
Visfatin [139–154]	Increased	Increased	Increased	?
CRP [31, 34–36, 40–46, 90, 155–161]	Increased	Increased	Increased	Increased
PAI-1 [31, 34–36, 42, 43, 98, 162]	Increased	Increased	Increased	Increased
IL-6 [98, 163–167]	Increased	Increased	Increased	Increased
TNF-𝛼 [43, 84, 100, 103, 104, 155, 163–167]	Increased	Increased	Increased	Increased