Adjunctive Sitagliptin Therapy in Postoperative Cardiac Surgery Patients: A Pilot Study

Table 3

Antihyperglycemic medication utilization.

Variable	Sitagliptin; (𝑛=30)	Placebo; (𝑛=32)	𝑃 value
Overall insulin utilization
Mean number of units over 4-day study period, 𝑛	13.2 ± 13.5	13.5 ± 12.6	0.942
Mean amount of dextrose utilized during study*, grams	4.8 ± 6.3	3.4 ± 3.4	0.307
Insulin utilization SD no. 1
Mean number of units, 𝑛	32.5 ± 26.5	34.0 ± 36.5	0.857
Mean amount of dextrose, grams	13.7 ± 11.2	7.0 ± 7.5	0.008
Insulin utilization SD no. 2
Mean number of units, 𝑛	10.1 ± 15.7	7.2 ± 11.5	0.411
Mean amount of dextrose, grams	1.4 ± 4.4	2.6 ± 7.0	0.437
Insulin utilization SD no. 3
Mean number of units, 𝑛	6.3 ± 12.1	4.5 ± 8.3	0.500
Mean amount of dextrose, grams	1.5 ± 6.6	1.3 ± 4.1	0.917
Insulin utilization SD no. 4
Mean number of units, 𝑛	5.7 ± 11.8	3.1 ± 5.2	0.319
Mean amount of dextrose, grams	1.4 ± 6.8	0.6 ± 1.6	0.593
Oral Agents
Percentage of subjects with home medications restarted SD no. 1	53.3%	34.4%	0.212
Percentage of subjects with home medications restarted SD no. 2	70%	50%	0.179
Percentage of subjects with home medications restarted SD no. 3	70%	59.4%	0.543
Percentage of subjects with home medications restarted SD no. 4	70%	65.6%	0.923

*Amount of dextrose infused in medications and/or continuous infusions.
SD: study day.