Regulation and Roles of Urocortins in the Vascular System
Figure 4
Effects of cyclooxygenase inhibitors on Ucn1- or Ucn2-induced IL-6 output in A7r5 aortic smooth muscle cells. Cells were treated in triplicate, with the mean of three independent experiments (an average in triplicate was considered ; three experiments ) shown in figures. Statistical analyses were performed using one-way ANOVA, followed by Scheffe’s F post hoc test. Cells were preincubated with medium containing indomethacin (INDO), NS-398 (NS), or vehicle for 30 min then incubated for 48 h with medium containing 100 nM Ucn1, Ucn2, or vehicle. * (compared with only Ucn1). # (compared with only Ucn2). Reproduction from [23] with permission of the publisher. Copyright 2006, The Endocrine Society.
