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International Journal of Endocrinology
Volume 2012 (2012), Article ID 919650, 7 pages
doi:10.1155/2012/919650
Review Article
Radiofrequency Ablation of Thyroid Nodules: Basic Principles and Clinical Application
Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea
Received 13 April 2012; Accepted 9 October 2012
Academic Editor: Ajai Kumar Srivastav
Copyright © 2012 Ji Hoon Shin et al. This is an open access paper distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- W. J. Moon, J. H. Baek, S. L. Jung et al., “Ultrasonography and the ultrasound-based management of thyroid nodules: consensus statement and recommendations,” Korean Journal of Radiology, vol. 12, no. 1, pp. 1–14, 2011. View at Publisher · View at Google Scholar · View at Scopus
- J. H. Baek, J. H. Lee, R. Valcavi, C. M. Pacella, H. Rhim, and D. G. Na, “Thermal ablation for benign thyroid nodules: radiofrequency and laser,” Korean Journal of Radiology, vol. 12, no. 5, pp. 525–540, 2011. View at Publisher · View at Google Scholar · View at Scopus
- E. J. Ha, J. H. Baek, and J. H. Lee, “The efficacy and complications of radiofrequency ablation of thyroid nodules,” Current Opinion in Endocrinology, Diabetes and Obesity, vol. 18, no. 5, pp. 310–314, 2011. View at Publisher · View at Google Scholar · View at Scopus
- L. J. Shemen and E. W. Strong, “Complications after total thyroidectomy,” Otolaryngology—Head and Neck Surgery, vol. 101, no. 4, pp. 472–475, 1989. View at Scopus
- E. Papini, R. Guglielmi, G. Bizzarri et al., “Treatment of benign cold thyroid nodules: a randomized clinical trial of percutaneous laser ablation versus levothyroxine therapy or follow-up,” Thyroid, vol. 17, no. 3, pp. 229–235, 2007. View at Publisher · View at Google Scholar · View at Scopus
- Y. J. Kim, J. H. Baek, E. J. Ha et al., “Cystic versus predominantly cystic thyroid nodules: efficacy of ethanol ablation and analysis of related factors,” European Radiology, vol. 22, no. 7, pp. 1573–1578, 2012. View at Publisher · View at Google Scholar · View at Scopus
- L. Hegedüs, “Therapy: a new nonsurgical therapy option for benign thyroid nodules?” Nature Reviews Endocrinology, vol. 5, no. 9, pp. 476–478, 2009. View at Publisher · View at Google Scholar · View at Scopus
- R. Diaz, “Thyroid: HIFU for thyroid nodule ablation,” Nature Reviews Endocrinology, vol. 7, article 631, 2011. View at Publisher · View at Google Scholar · View at Scopus
- O. Esnault, B. Franc, F. Ménégaux et al., “High-intensity focused ultrasound ablation of thyroid nodules: first human feasibility study,” Thyroid, vol. 21, no. 9, pp. 965–973, 2011. View at Publisher · View at Google Scholar · View at Scopus
- B. Feng, P. Liang, Z. Cheng et al., “Ultrasound-guided percutaneous microwave ablation of benign thyroid nodules: experimental and clinical studies,” European Journal of Endocrinology, vol. 166, no. 6, pp. 1031–1037, 2012. View at Publisher · View at Google Scholar · View at Scopus
- H. Rhim, S. N. Goldberg, G. D. Dodd et al., “Essential techniques for successful radio-frequency thermal ablation of malignant hepatic tumors,” Radiographics, vol. 21, pp. S17–S35, 2001. View at Scopus
- S. N. Goldberg, “Radiofrequency tumor ablation: principles and techniques,” European Journal of Ultrasound, vol. 13, no. 2, pp. 129–147, 2001. View at Publisher · View at Google Scholar · View at Scopus
- S. N. Goldberg, G. S. Gazelle, and P. R. Mueller, “Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance,” American Journal of Roentgenology, vol. 174, no. 2, pp. 323–331, 2000. View at Scopus
- J. H. Baek, H. J. Jeong, Y. S. Kim, M. S. Kwak, and D. Lee, “Radiofrequency ablation for an autonomously functioning thyroid nodule,” Thyroid, vol. 18, no. 6, pp. 675–676, 2008. View at Publisher · View at Google Scholar · View at Scopus
- J. H. Baek, Y. S. Kim, D. Lee, J. Y. Huh, and J. H. Lee, “Benign predominantly solid thyroid nodules: prospective study of efficacy of sonographically guided radiofrequency ablation versus control condition,” American Journal of Roentgenology, vol. 194, no. 4, pp. 1137–1142, 2010. View at Publisher · View at Google Scholar · View at Scopus
- M. Deandrea, P. Limone, E. Basso et al., “US-guided percutaneous radiofrequency thermal ablation for the treatment of solid benign hyperfunctioning or compressive thyroid nodules,” Ultrasound in Medicine and Biology, vol. 34, no. 5, pp. 784–791, 2008. View at Publisher · View at Google Scholar · View at Scopus
- W. K. Jeong, J. H. Baek, H. Rhim et al., “Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients,” European Radiology, vol. 18, no. 6, pp. 1244–1250, 2008. View at Publisher · View at Google Scholar · View at Scopus
- Y. S. Kim, H. Rhim, K. Tae, D. W. Park, and S. T. Kim, “Radiofrequency ablation of benign cold thyroid nodules: initial clinical experience,” Thyroid, vol. 16, no. 4, pp. 361–367, 2006. View at Publisher · View at Google Scholar · View at Scopus
- J. H. Lee, Y. S. Kim, D. Lee, H. Choi, H. Yoo, and J. H. Baek, “Radiofrequency ablation (RFA) of benign thyroid nodules in patients with incompletely resolved clinical problems after ethanol ablation (EA),” World Journal of Surgery, vol. 34, no. 7, pp. 1488–1493, 2010. View at Publisher · View at Google Scholar · View at Scopus
- S. Spiezia, R. Garberoglio, F. Milone et al., “Thyroid nodules and related symptoms are stably controlled two years after radiofrequency thermal ablation,” Thyroid, vol. 19, no. 3, pp. 219–225, 2009. View at Publisher · View at Google Scholar · View at Scopus
- J. Y. Sung, Y. S. Kim, H. Choi, J. H. Lee, and J. H. Baek, “Optimum first-line treatment technique for benign cystic thyroid nodules: ethanol ablation or radiofrequency ablation?” American Journal of Roentgenology, vol. 196, no. 2, pp. W210–W214, 2011. View at Publisher · View at Google Scholar · View at Scopus
- J. H. Baek, W. J. Moon, Y. S. Kim, J. H. Lee, and D. Lee, “Radiofrequency ablation for the treatment of autonomously functioning thyroid nodules,” World Journal of Surgery, vol. 33, no. 9, pp. 1971–1977, 2009. View at Publisher · View at Google Scholar · View at Scopus
- J. H. Baek, Y. S. Kim, J. Y. Sung, H. Choi, and J. H. Lee, “Locoregional control of metastatic well-differentiated thyroid cancer by ultrasound-guided radiofrequency ablation,” American Journal of Roentgenology, vol. 197, no. 2, pp. W331–W336, 2011. View at Publisher · View at Google Scholar · View at Scopus
- D. E. Dupuy, J. M. Monchik, C. Decrea, and L. Pisharodi, “Radiofrequency ablation of regional recurrence from well-differentiated thyroid malignancy,” Surgery, vol. 130, no. 6, pp. 971–977, 2001. View at Publisher · View at Google Scholar · View at Scopus
- J. M. Monchik, G. Donatini, J. Iannuccilli, and D. E. Dupuy, “Radiofrequency ablation and percutaneous ethanol injection treatment for recurrent local and distant well-differentiated thyroid carcinoma,” Annals of Surgery, vol. 244, no. 2, pp. 296–304, 2006. View at Publisher · View at Google Scholar · View at Scopus
- K. W. Park, J. H. Shin, B. K. Han, E. Y. Ko, and J. H. Chung, “Inoperable symptomatic recurrent thyroid cancers: preliminary result of radiofrequency ablation,” Annals of Surgical Oncology, vol. 18, no. 9, pp. 2564–2568, 2011. View at Publisher · View at Google Scholar · View at Scopus
- S. Spiezia, R. Garberoglio, C. Di Somma et al., “Efficacy and safety of radiofrequency thermal ablation in the treatment of thyroid nodules with pressure symptoms in elderly patients,” Journal of the American Geriatrics Society, vol. 55, no. 9, pp. 1478–1479, 2007. View at Publisher · View at Google Scholar · View at Scopus
- Y. S. Jin, J. H. Baek, S. K. Yoon et al., “One-step ethanol ablation of viscous cystic thyroid nodules,” American Journal of Roentgenology, vol. 191, no. 6, pp. 1730–1733, 2008. View at Publisher · View at Google Scholar · View at Scopus
- D. G. Na, J. H. Lee, S. L. Jung et al., “Radiofrequency ablation of benign Thyroid nodules and recurrent Thyroid cancers: consensus statement and recommendations,” Korean Journal of Radiology, vol. 13, no. 2, pp. 117–125, 2012. View at Publisher · View at Google Scholar · View at Scopus
- E. Papini, R. Guglielmi, G. Hosseim et al., “Ultrasound-guided laser ablation of incidental papillary thyroid microcarcinoma: a potential therapeutic approach in patients at surgical risk,” Thyroid, vol. 21, no. 8, pp. 917–920, 2011. View at Publisher · View at Google Scholar · View at Scopus
- D. G. Na, J.-H. Kim, J. Y. Sung et al., “Core-needle biopsy is more useful than repeat fine-needle aspiration in thyroid nodules read as nondiagnostic or atypia of undetermined significance by the bethesda system for reporting thyroid cytopathology,” Thyroid, vol. 22, no. 5, pp. 468–475, 2012. View at Publisher · View at Google Scholar · View at Scopus
- J. Y. Sung, D. G. Na, K. S. Kim et al., “Diagnostic accuracy of fine-needle aspiration versus core-needle biopsy for the diagnosis of thyroid malignancy in a clinical cohort,” European Radiology, vol. 22, no. 7, pp. 1564–1572, 2012. View at Publisher · View at Google Scholar · View at Scopus
- O. Algin, E. Algin, G. Gokalp et al., “Role of duplex power Doppler ultrasound in differentiation between malignant and benign thyroid nodules,” Korean Journal of Radiology, vol. 11, no. 6, pp. 594–602, 2010. View at Publisher · View at Google Scholar · View at Scopus
- S. H. Kim, C. S. Park, S. L. Jung et al., “Observer variability and the performance between faculties and residents: US criteria for benign and malignant thyroid nodules,” Korean Journal of Radiology, vol. 11, no. 2, pp. 149–155, 2010. View at Publisher · View at Google Scholar · View at Scopus
- Y. H. Lee, D. W. Kim, H. S. In et al., “Differentiation between benign and malignant solid thyroid nodules using an US classification system,” Korean Journal of Radiology, vol. 12, no. 5, pp. 559–567, 2011. View at Publisher · View at Google Scholar · View at Scopus
- W. J. Moon, L. J. So, H. L. Jeong et al., “Benign and malignant thyroid nodules: US differentiation—multicenter retrospective study,” Radiology, vol. 247, no. 3, pp. 762–770, 2008. View at Publisher · View at Google Scholar · View at Scopus
- H. K. Lim, J. H. Lee, E. J. Ha, J. Y. Sung, J. K. Kim, and J. H. Baek, “Radiofrequency ablation of benign nonfunctioning thyroid nodules: 4-year follow-up results in 111 patients,” European Radiology. In press.
- S. W. Jang, J. H. Baek, J. K. Kim et al., “How to manage the patients with unsatisfactory results after ethanol ablation for thyroid nodules: role of radiofrequency ablation,” European Journal of Radiology, vol. 81, no. 5, pp. 905–910, 2011. View at Publisher · View at Google Scholar · View at Scopus
- J. Y. Huh, J. H. Baek, H. Choi, J. K. Kim, and J. H. Lee, “Symptomatic benign thyroid nodules: efficacy of additional radiofrequency ablation treatment session—prospective randomized study,” Radiology, vol. 263, no. 3, pp. 909–916, 2012. View at Publisher · View at Google Scholar · View at Scopus
- J. H. Baek, J. H. Lee, J. Y. Sung et al., “Complications encountered in the treatment of benign thyroid nodules with us-guided radiofrequency ablation: a multicenter study,” Radiology, vol. 262, no. 1, pp. 335–342, 2012. View at Publisher · View at Google Scholar · View at Scopus
- R. Valcavi, F. Riganti, A. Bertani, D. Formisano, and C. M. Pacella, “Percutaneous laser ablation of cold benign thyroid nodules: a 3-year follow-up study in 122 patients,” Thyroid, vol. 20, no. 11, pp. 1253–1261, 2010. View at Publisher · View at Google Scholar · View at Scopus
- F. Giovagnorio and C. Martinoli, “Sonography of the cervical vagus nerve: normal appearance and abnormal findings,” American Journal of Roentgenology, vol. 176, no. 3, pp. 745–749, 2001. View at Scopus
- Y. S. Kim, H. Rhim, D. Choi, and H. K. Lim, “Does artificial ascites induce the heat-sink phenomenon during percutaneous radiofrequency ablation of the hepatic subcapsular area?: an in vivo experimental study using a rabbit model,” Korean Journal of Radiology, vol. 10, no. 1, pp. 43–50, 2009. View at Publisher · View at Google Scholar · View at Scopus
- D. G. Na, J. H. Lee, S. M. Kim, H. K. Lim, and J. H. Baek, “Unidirectional ablation electrode to minimize thermal injury during radiofrequency ablation: an experimental study in an ex vivo bovine liver model,” Journal of Vascular and Interventional Radiology, vol. 22, no. 7, pp. 935–940, 2011. View at Publisher · View at Google Scholar · View at Scopus
- S. Mulier, P. Mulier, Y. Ni et al., “Complications of radiofrequency coagulation of liver tumours,” British Journal of Surgery, vol. 89, no. 10, pp. 1206–1222, 2002. View at Publisher · View at Google Scholar · View at Scopus
- M. L. Jeong, K. H. Joon, H. K. Se et al., “Comparison of wet radiofrequency ablation with dry radiofrequency ablation and radiofrequency ablation using hypertonic saline preinjection: ex vivo bovine liver,” Korean Journal of Radiology, vol. 5, no. 4, pp. 258–265, 2004. View at Scopus
- J. Cha, D. Choi, M. W. Lee et al., “Radiofrequency ablation zones in Ex vivo bovine and in vivo porcine livers: comparison of the use of internally cooled electrodes and internally cooled wet electrodes,” CardioVascular and Interventional Radiology, vol. 32, no. 6, pp. 1235–1240, 2009. View at Publisher · View at Google Scholar · View at Scopus
- D. W. Kim, “Sonography-guided ethanol ablation of a remnant solid component after radio-frequency ablation of benign solid thyroid nodules: a preliminary study,” American Journal of Neuroradiology, vol. 33, no. 6, pp. 1139–1143, 2012. View at Publisher · View at Google Scholar · View at Scopus
- Y. J. Zhang, H. H. Liang, M. S. Chen et al., “Hepatocellular carcinoma treated with radiofrequency ablation with or without ethanol injection: a prospective randomized trial,” Radiology, vol. 244, no. 2, pp. 599–607, 2007. View at Publisher · View at Google Scholar · View at Scopus