Clinical and Laboratorial Features That May Differentiate 46,XY DSD due to Partial Androgen Insensitivity and 5α-Reductase Type 2 Deficiency

Table 4

Data from 7 families with 5α-reductase type 2 deficiency, 5 families with PAIS, and 39 isolated undetermined cases.

		5α-reductase type 2 deficiency	PAIS	Undetermined	𝑃 value*
Parental consanguinity	+	5	2	2	𝑃=0.00005
	−	2	3	37
Familial recurrence	+	3	5	13	𝑃=0.02
	−	4	0	26
Ambiguous genitalia Sinnecker et al. [9]	2	1	3	29	𝑃=0.0004
	3	7	2	10
	4	1	5	0
Ambiguous genitalia Ahmed et al. [10]	<3.5	6	7	4	𝑃=0.00003
	≥3.5	3	3	35

*Chi-square test.