Research Article
Clinical and Laboratorial Features That May Differentiate 46,XY DSD due to Partial Androgen Insensitivity and 5α-Reductase Type 2 Deficiency
Table 5
Data from 9 patients with 5α-reductase type 2 deficiency, 10 patients with PAIS, and 39 isolated undetermined cases.
| | 5α-reductase type 2 deficiency | PAIS | Undetermined | value* |
| | Age at first consultation (yr) | 9.6 ± 7.5
(0.05–18.2) | 8.0 ± 10.0
(0.2–28.8) | 2.5 ± 4.5
(0,02–20,7) | | | Birth weight (g) | 2890 ± 290
(2600–3500) | 3100 ± 400
(2630–3950) | 2470 ± 460
(1700–3000) | | | Birth length (cm) | 48 ± 1
(47–50) | 48 ± 2
(46–51) | 46 ± 3
(39–50) | | | Penile length (z) | −4.0 ± 0.4
(−4.6–−3.1) | −6.0 ± 2.1
(−8.7–−2.7) | −3.2 ± 1.2
(−6.6–−1.1) | | | T (ng/mL) | 4.6 ± 4.1
(1.8–13.6) | 4.5 ± 4.4
(1.7–15.0) | 2.6 ± 1.4
(1.5–9.1) | | | Δ4 (ng/mL) | 1.4 ± 0.4
(0.8–1.9) | 1.1 ± 0.4
(0.7–1.9) | 1.2 ± 0.3
(0.7–1.7) | | | T/Δ4 ratio | 3.0 ± 1.9
(1.5–7.2) | 3.6 ± 1.9
(2.1–7.9) | 2.7 ± 0.9
(1.8–7.0) | | | T/DHT ratio | 54 ± 19
(28–82) | 51 ± 15
(32–72) | 14 ± 16
(1–95) | |
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*Kruskal-Wallis test.
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