Review Article

The Role of Vitamin D Deficiency in the Incidence, Progression, and Complications of Type 1 Diabetes Mellitus

Table 1

VDR gene polymorphism and type 1 DM.

Population VDR polymorphism associated with IDDM

BangladeshFokI, BsmI, ApaI, TaqI
BrazilNo association
ChileBsmI, ApaI, TaqI¹
Croatia Tru91, Fok
FinlandNo association
GermanyTakI, ApaI, BsmI¹, Tru
GreeceFokI, BsmI, ApaI, TaqI
HungaryBsmI, ApaI, Tru914
India NorthernFokI, TaqI
India SouthernBsmI
Italy No association
IranTaqI
Japan
BsmI, FokI
Norway No association
Polish
No association
PortugalNo association
RomaniaNo association
SpainFokI
Taiwan BsmI, ApaI
TurkeyFokI
United StatesNo association
United KingdomNo association

Combined.
²Dalmatian population.
³In one study, in combination with TruI, VDR polymorphisms were protective against DM type I.
4Combined, only in girls.