Trunk Fat Negatively Influences Skeletal and Testicular Functions in Obese Men: Clinical Implications for the Aging Male

Table 1

Biochemical and hormonal characteristics of the patients according to different BMI. Values are expressed as means ± SD.

	BMI < 30 (𝑛=20)	BMI 30 ≤ 35 (𝑛=22)	BMI 35 ≤ 40 (𝑛=22)	BMI > 40 (𝑛=22)
BMI	27±1.2	32±1.6^∗∗	38±1.5^∗∗∗	44±4^∗∗∗	^∗∗𝑃<0.001; ^∗∗∗𝑃<0.0001
Mean age (yrs)	51±12	42±18	47±10	46±13	—
Total chol. (mg/dL)	195±43	197±42	215±34	202±39	—
HDL (mg/dL)	42±10	42±7	41±6	44±4	—
TGL (mg/dL)	119±53	131±54	126±52	151±58	—
Fibrinogen (mg/dL)	263±81	303±70	366±76	402±133^∗∗	^∗∗𝑃<0.001
CRP (ng/mL)	3±1.5	3±1.8	4±2.4	5.5±2.1^∗∗	^∗∗𝑃<0.001
HOMA	2.7±1.4	4.4±2.1^∗∗∗	5.7±2.5^∗∗∗	6.4±2.2^∗∗∗	^∗∗∗𝑃<0.0001
OSCA (μg/L)	25.34±10.7	19±10.1	16.6±9.1^∗	12.5±7.1^∗∗∗	^∗𝑃<0.01; ^∗∗∗𝑃<0.0001
SHBG (nmol/L)	25±10	24±13	25±10	27±12	—
PTH (pg/mL)	38±14	39±13	39±13	49±14	—
Vitamin D (ng/mL)	29±7	23±5^∗	19±8^∗∗	14±9^∗∗∗	^∗𝑃<0.01; ^∗∗𝑃<0.001; ^∗∗∗𝑃<0.0001
17β-E2 (pg/mL)	29±11	32±9	31±13	35±16	—
Testosterone (ng/mL)	4.4±1.06	4.5±1.24	3.17±1.32^∗	2.69±1.1^∗∗	^∗𝑃<0.01; ^∗∗𝑃<0.001
Trunk fat (%)	25.5±6.6	33.74±6.1^∗∗∗	37.11±5.2^∗∗∗	41.86±7.1^∗∗∗	^∗∗∗𝑃<0.0001