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International Journal of Endocrinology
Volume 2013 (2013), Article ID 285729, 9 pages
http://dx.doi.org/10.1155/2013/285729
Research Article

Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes

Department of Endocrinology, Jishuitan Hospital, Beijing 100035, China

Received 21 September 2012; Revised 22 November 2012; Accepted 16 December 2012

Academic Editor: Maria L. Dufau

Copyright © 2013 Hai-ling Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. F. Heinemann, “Osteoporosis: an overview of the National Osteoporosis Foundation clinical practice guide,” Geriatrics, vol. 55, no. 5, pp. 31–36, 2000. View at Scopus
  2. G. Salkeld, I. D. Cameron, R. G. Cumming et al., “Quality of life related to fear of falling and hip fracture in older women: a time trade off study,” British Medical Journal, vol. 320, no. 7231, pp. 341–345, 2000. View at Scopus
  3. P. R. Ebeling, “Osteoporosis in men,” The New England Journal of Medicine, vol. 358, no. 14, pp. 1474–1430, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. R. A. Adler, “Osteoporosis in men: insights for the clinician,” Therapeutic Advances in Musculoskeletal Disease, vol. 3, pp. 191–200, 2011.
  5. R. Burge, B. Dawson-Hughes, D. H. Solomon, J. B. Wong, A. King, and A. Tosteson, “Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025,” Journal of Bone and Mineral Research, vol. 22, no. 3, pp. 465–475, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. E. Bass, D. D. French, D. D. Bradham, and L. Z. Rubenstein, “Risk-adjusted mortality rates of elderly veterans with hip fractures,” Annals of Epidemiology, vol. 17, no. 7, pp. 514–519, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. H. X. Jiang, S. R. Majumdar, D. A. Dick et al., “Development and initial validation of a risk score for predicting in-hospital and 1-year mortality in patients with hip fractures,” Journal of Bone and Mineral Research, vol. 20, no. 3, pp. 494–500, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. L. C. Hofbauer, C. C. Brueck, S. K. Singh, and H. Dobnig, “Osteoporosis in patients with diabetes mellitus,” Journal of Bone and Mineral Research, vol. 22, no. 9, pp. 1317–1328, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Saller, S. Maggi, G. Romanato, P. Tonin, and G. Crepaldi, “Diabetes and osteoporosis,” Aging - Clinical and Experimental Research, vol. 20, no. 4, pp. 280–289, 2008. View at Scopus
  10. V. Rakic, W. A. Davis, S. A. P. Chubb, F. M. A. Islam, R. L. Prince, and T. M. E. Davis, “Bone mineral density and its determinants in diabetes: The Fremantle Diabetes Study,” Diabetologia, vol. 49, no. 5, pp. 863–871, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Adami, “Bone health in diabetes: considerations for clinical management,” Current Medical Research and Opinion, vol. 25, no. 5, pp. 1057–1072, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. S. A. Abdulameer, S. A. Sulaiman, M. A. Hassali, K. Subramaniam, and M. N. Sahib, “Osteoporosis and type 2 diabetes mellitus: what do we know, and what can we do?” Patient Preference and Adherence, vol. 6, pp. 435–448, 2012.
  13. T. Yamaguchi and Y. Sugimoto, “Bone metabolism and fracture risk in type 2 diabetes mellitus,” Endocrine Journal, vol. 58, pp. 613–624, 2011.
  14. L. Xu, M. Cheng, X. Liu, P. Shan, and H. Gao, “Bone mineral density and its related factors in elderly male chinese patients with type 2 diabetes,” Archives of Medical Research, vol. 38, no. 2, pp. 259–264, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Xia, Y. Zhong, G. Huang, Y. Chen, H. Shi, and Z. Zhang, “The relationship between insulin resistance and osteoporosis in elderly male type 2 diabetes mellitus and diabetic nephropathy,” Annales d'Endocrinologie, vol. 73, no. 6, pp. 546–551, 2012.
  16. World Health Organization, “Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia,” Report of a WHO/IDF Consultation, 2006.
  17. World Health Organization, “Assessment of fracture risk and its application to screening for postmenopausal osteoporosis,” Technical Report Series, vol. 843, pp. 1–129, 1994.
  18. T. Majima, Y. Komatsu, T. Yamada et al., “Decreased bone mineral density at the distal radius, but not at the lumbar spine or the femoral neck, in Japanese type 2 diabetic patients,” Osteoporosis International, vol. 16, no. 8, pp. 907–913, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. K. F. Moseley, “Type 2 diabetes and bone fractures,” Current Opinion in Endocrinology, Diabetes and Obesity, vol. 19, pp. 128–1135, 2012.
  20. F. Afshinnia, S. Chacko, and T. Zahedi, “Association of lower serum cholesterol levels with higher risk of osteoporosis in type 2 diabetes,” Endocrine Practice, vol. 13, no. 6, pp. 620–628, 2007. View at Scopus
  21. R. M. Sta and J. T. Li-Yu, “Investigation of the relationship between type 2 diabetes and osteoporosis using Bayesian inference,” Journal of Clinical Densitometry, vol. 10, no. 4, pp. 386–390, 2007. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Räkel, O. Sheehy, E. Rahme, and J. LeLorier, “Osteoporosis among patients with type 1 and type 2 diabetes,” Diabetes and Metabolism, vol. 34, no. 3, pp. 193–205, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. I. Anaforoglu, A. Nar-Demirer, N. Bascil-Tutuncu, and M. E. Ertorer, “Prevalence of osteoporosis and factors affecting bone mineral density among postmenopausal Turkish women with type 2 diabetes,” Journal of Diabetes and Its Complications, vol. 23, no. 1, pp. 12–17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. A. Montagnani, S. Gonnelli, M. Alessandri, and R. Nuti, “Osteoporosis and risk of fracture in patients with diabetes: an update,” Aging—Clinical and Experimental Research, vol. 23, no. 2, pp. 84–90, 2011. View at Scopus
  25. L. J. Melton, C. L. Leibson, S. J. Achenbach, T. M. Therneau, and S. Khosla, “Fracture risk in type 2 diabetes: update of a population-based study,” Journal of Bone and Mineral Research, vol. 23, no. 8, pp. 1334–1342, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Espallargues, L. Sampietro-Colom, M. D. Estrada et al., “Identifying bone-mass-related risk factors for fracture to guide bone densitometry measurements: a systematic review of the literature,” Osteoporosis International, vol. 12, no. 10, pp. 811–822, 2001. View at Publisher · View at Google Scholar · View at Scopus
  27. G. Barrera, D. Bunout, V. Gattás, M. P. De La Maza, L. Leiva, and S. Hirsch, “A high body mass index protects against femoral neck osteoporosis in healthy elderly subjects,” Nutrition, vol. 20, no. 9, pp. 769–771, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. P. Vestergaard, “Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes—a meta-analysis,” Osteoporosis International, vol. 18, no. 4, pp. 427–444, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. A. V. Schwartz, D. E. Sellmeyer, E. S. Strotmeyer et al., “Diabetes and bone loss at the hip in older black and white adults,” Journal of Bone and Mineral Research, vol. 20, no. 4, pp. 596–603, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. D. M. Black, S. R. Cummings, H. K. Genant, M. C. Nevitt, L. Palermo, and W. Browner, “Axial and appendicular bone density predict fractures in older women,” Journal of Bone and Mineral Research, vol. 7, no. 6, pp. 633–638, 1992. View at Scopus
  31. B. E. C. Nordin, “Redefining osteoporosis,” Calcified Tissue International, vol. 83, no. 6, pp. 365–367, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. S. Rasul, A. Ilhan, L. Wagner, A. Luger, and A. Kautzky-Willer, “Diabetic neuropathy relates to bone metabolism and markers of bone turnover in elderly patients with type 2 diabetes: greater effects in male patients,” Gender Medicine, vol. 9, pp. 187–196, 2012.
  33. D. L. Chau, S. V. Edelman, and M. Chandran, “Osteoporosis and diabetes,” Current Diabetes Reports, vol. 3, no. 1, pp. 37–42, 2003. View at Scopus
  34. P. Garnero, “Markers of bone turnover for the prediction of fracture risk,” Osteoporosis International, vol. 11, pp. S55–S65, 2000.
  35. D. C. Bauer, P. Garnero, M. C. Hochberg et al., “Pretreatment levels of bone turnover and the antifracture efficacy of alendronate: the fracture intervention trial,” Journal of Bone and Mineral Research, vol. 21, no. 2, pp. 292–299, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. L. J. Melton, C. S. Crowson, W. M. O'Fallon, H. W. Wahner, and B. L. Riggs, “Relative contributions of bone density, bone turnover, and clinical risk factors to long-term fracture prediction,” Journal of Bone and Mineral Research, vol. 18, no. 2, pp. 312–318, 2003. View at Publisher · View at Google Scholar · View at Scopus
  37. M. Inaba, “Secondary osteoporosis: thyrotoxicosis, rheumatoid arthritis, and diabetes mellitus,” Journal of Bone and Mineral Metabolism, vol. 22, no. 4, pp. 287–292, 2004. View at Scopus
  38. A. Amano and S. Kawai, “Diabetes and oral osteoporosis,” Clinical Calcium, vol. 17, no. 2, pp. 186–191, 2007. View at Scopus
  39. A. M. Inzerillo and S. Epstein, “Osteoporosis and diabetes mellitus,” Reviews in Endocrine & Metabolic Disorders, vol. 5, pp. 261–268, 2004.
  40. D. M. S. L. Cutrim, F. A. Pereira, F. J. A. de Paula, and M. C. Foss, “Lack of relationship between glycemic control and bone mineral density in type 2 diabetes mellitus,” Brazilian Journal of Medical and Biological Research, vol. 40, no. 2, pp. 221–227, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. F. Gregorio, S. Cristallini, F. Santeusanio, P. Filipponi, and P. Fumelli, “Osteopenia associated with non-insulin-dependent diabetes mellitus: what are the causes?” Diabetes Research and Clinical Practice, vol. 23, no. 1, pp. 43–54, 1994. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Yamaguchi and T. Sugimoto, “Calcium homeostasis and osteoporosis in diabetes mellitus and the metabolic syndrome,” Clinical Calcium, vol. 18, no. 7, pp. 904–911, 2008. View at Scopus
  43. C. Meier, T. V. Nguyen, D. J. Handelsman et al., “Endogenous sex hormones and incident fracture risk in older men: The Dubbo Osteoporosis Epidemiology Study,” Archives of Internal Medicine, vol. 168, no. 1, pp. 47–54, 2008. View at Publisher · View at Google Scholar · View at Scopus
  44. H. A. Fink, S. K. Ewing, K. E. Ensrud et al., “Association of testosterone and estradiol deficiency with osteoporosis and rapid bone loss in older men,” Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 10, pp. 3908–3915, 2006. View at Publisher · View at Google Scholar · View at Scopus
  45. A. C. Looker and M. E. Mussolino, “Serum 25-hydroxyvitamin D and hip fracture risk in older U.S. white adults,” Journal of Bone and Mineral Research, vol. 23, no. 1, pp. 143–150, 2008. View at Publisher · View at Google Scholar · View at Scopus
  46. L. Xian, X. Wu, L. Pang, et al., “Matrix IGF-1 maintains bone mass activation in mesenchymal stem cells,” Nature Medicine, vol. 18, no. 7, pp. 1095–1101, 2012.
  47. B. L. Riggs, L. J. Melton, R. A. Robb et al., “A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men,” Journal of Bone and Mineral Research, vol. 23, no. 2, pp. 205–214, 2008. View at Publisher · View at Google Scholar · View at Scopus
  48. K. M. Thrailkill, C. K. Lumpkin, R. C. Bunn, S. F. Kemp, and J. L. Fowlkes, “Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues,” American Journal of Physiology, vol. 289, no. 5, pp. E735–E745, 2005. View at Publisher · View at Google Scholar · View at Scopus
  49. D. A. De Luis Román, R. Aller, J. L. Perez Castrillon et al., “Effects of dietary intake and life style on bone density in patients with diabetes mellitus type 2,” Annals of Nutrition and Metabolism, vol. 48, no. 3, pp. 141–145, 2004. View at Publisher · View at Google Scholar · View at Scopus
  50. E. M. C. Lau, P. C. Leung, T. Kwok et al., “The determinants of bone mineral density in Chinese men—results from Mr. Os (Hong Kong), the first cohort study on osteoporosis in Asian men,” Osteoporosis International, vol. 17, no. 2, pp. 297–303, 2006. View at Publisher · View at Google Scholar · View at Scopus