Review Article

Comprehensive Literature Review: Recent Advances in Diagnosing and Managing Patients with Poorly Differentiated Thyroid Carcinoma

Table 1

Prevalence of genetic alterations in patients with various thyroid carcinomas.

Altered genePDTCPTCFTCATC

RET/PTC
0%20%0%0%
TP53
20–30%0%0%65–70%
BRAF
15%45%0%20–25%
RAS
30–35%10–15%45%50–55%
β-catenin
20–25%0%0%65%
PAX8 : PPARγ
0%0%35%0%

PDTC: poorly differentiated thyroid carcinoma.
PTC: papillary thyroid carcinoma.
FTC: follicular thyroid carcinoma.
ATC: anaplastic thyroid carcinoma.