Improved Glucose-Stimulated Insulin Secretion by Selective Intraislet Inhibition of Angiotensin II Type 1 Receptor Expression in Isolated Islets of db/db Mice
Figure 4
Effects of AT1R silencing on PI3-K(85) and p-Akt2 expression. Islets of db/db mice were transfected with Ad-si AT1R, Ad-siControl, or Mock and cells were cultured for 72 h prior to quantitative immunoblot evaluation. Results are represented as mean ± SD for six independent experiments. * versus Ad-siControl.