International Journal of Endocrinology

Research Article

Association between Sleep Disruption and Levels of Lipids in Caucasians with Type 2 Diabetes

Table 3

Standard and hierarchical multiple regression analyses predicting the natural log glucose and log HbA₁c (Table 3(a)), SBP and DBP (Table 3(b)), total cholesterol and LDL (Table 3(c)), and Log TG and HDL (Table 3(d)), from sleep duration and sleep quality.

(a)


Outcome: Log glucose			Outcome: Log HbA₁c
	Model 1 (unadjusted)	Model 2 (adjusted)*		Model 1 (unadjusted)	Model 2 (adjusted)*

Sleep duration (h)			Sleep duration (h)
	0.184	0.21		0.038	−0.024
Part correlation	0.11	0.13	Part correlation	0.022	−0.014
	0.25	0.19		0.813	0.886

Sleep quality (PSQI score)			Sleep quality (PSQI score)
	0.187	0.24		0.107	0.038
Part correlation	0.11	0.14	Part correlation	0.064	0.021
	0.24	0.16		0.499	0.826

(b)


Outcome: SBP			Outcome: DBP
	Model 1 (unadjusted)	Model 2 (adjusted)*		Model 1 (unadjusted)	Model 2 (adjusted)*

Sleep duration (h)			Sleep duration (h)
	0.167	0.076		0.084	0.051
Part correlation	0.1	0.043	Part correlation	0.05	0.029
	0.284	0.64		0.593	0.759

Sleep quality (PSQI score)			Sleep quality (PSQI score)
	0.32	0.194		0.187	0.126
Part correlation	0.92	0.107	Part correlation	0.112	0.07
	0.041	0.249		0.237	0.465

(c)


Outcome: total cholesterol			Outcome: LDL
	Model 1 (unadjusted)	Model 2 (adjusted)*		Model 1 (unadjusted)	Model 2 (adjusted)*

Sleep duration (h)			Sleep duration (h)
	0.506	0.561		0.294	0.393
Part correlation	0.302	0.322	Part correlation	0.176	0.226
	0.001	0.001		0.065	0.016

Sleep quality (PSQI score)			Sleep quality (PSQI score)
	0.617	0.675		0.334	0.438
Part correlation	0.369	0.372	Part correlation	0.2	0.242
	0.001	0.002		0.036	0.01

(d)


Outcome: HDL			Outcome: Log TG
	Model 1 (unadjusted)	Model 2 (adjusted)*		Model 1 (unadjusted)	Model 2 (adjusted)*

Sleep duration (h)			Sleep duration (h)
	0.34	0.304		0.142	0.122
Part correlation	0.203	0.174	Part correlation	0.085	0.07
	0.032	0.06		0.364	0.453

Sleep quality (PSQI score)			Sleep quality (PSQI score)
	0.285	0.214		0.285	0.279
Part correlation	0.17	0.118	Part correlation	0.17	0.154
	0.072	0.201		0.07	0.101

Bold face type indicates statistically significant results. *Model 2 is adjusted for age, sex, BMI, and treatment with lipid-lowering agent.