Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism

Figure 1

Anandamide synthesis pathway. Pathways involved in the synthesis of anandamide from dietary linoleic acid and arachidonic acid, via the addition of either phosphatidyl ethanolamide or ethanolamide, the latter also resulting in phosphatidic acid production. Adapted from the works of Salem et al. [31], Sugiura [32], Cravatt et al. [33], Cadas et al. [34], and Okamoto et al. [35].