Table 4: Multivariate predictors of ΔHbA1c after sulfonylurea treatment.

Independent variablesModel 1Model 2

TCF7L2 genotype 0.0060.002
Sulfonylurea type0.4190.028
TCF7L2 genotype * sulfonylurea type0.023
HbA1c baseline<0.001<0.001
Age0.8010.713
Gender0.3850.335
BMI0.2460.240
Sulfonylurea dose0.2180.380

Coding of the variables: TCF7L2 genotype: CC-0, CT + TT-1; sulfonylurea type: gliclazide-1, other sulfonylureas-2; gender: male-1, female-2.