Table 1: Baseline characteristics of 402 overweight/obese children according to serum TSH.

Serum TSH value
≤4 mIU/L ( )>4 mIU/L ( )

TSH, mIU/L2.42 (2.33–2.52)4.74 (4.52–4.95)<0.0001
Age, years 10.7 (10.3–11.1)10.9 (10.0–11.2)0.46
Male gender, (%)175 (55.7)55 (62.5)0.35
Prepubertal, (%)159 (50.6)58 (65.9)0.56
Weight, Kg61 (59–63)60 (55–65)0.70
Height, cm149 (147–152)149 (144–153)0.80
BMI, Kg/m226.3 (25.7–26.8)26.3 (25.2–27.3)0.75
BMI-SDS2.0 (1.94–2.2)2.0 (1.9–2.2)0.80
Waist circumference, cm87 (84–90)89 (87–90)0.26
Systolic blood pressure, mmHg109 (107–110)110 (107–112)0.88
Diastolic blood pressure, mmHg69 (68–70)70 (67–72)0.82
Triglycerides, mg/dL99 (90–108)119 (103–135)<0.01
Total cholesterol, mg/dL160 (156–165)176 (166–186)<0.01
HDL-C, mg/dL47 (46–49)45 (43–48)0.30
Fasting glucose, mmol/L4.71 (4.64–4.78)4.67 (4.58–4.75)0.48
Insulin, mU/L 16.0 (15.0–18.0)19.3 (16.5–22.0)<0.05
HOMA-IR values3.62 (3.22–4.0)4.0 (3.4–4.6)<0.05
ALT, IU/L31 (28–35)52 (36–68)<0.01
GGT, IU/L17 (16–19)22 (18–26)<0.01
FT3, pg/mL4.26 (4.18–4.35)4.35 (4.26–4.42)0.14
FT4, ng/dL1.18 (1.15–1.22)1.18 (1.12–1.22)0.76

Data are expressed as (%), mean or geometric mean (95% confidence intervals).
TSH: thyroid-stimulating hormone; BMI: body mass index; BMI-SDS: BMI-SD score; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; ALT: alanine aminotransferase; GGT: gamma-glutamyl transferase; FT3: free triiodothyronine; FT4: free thyroxine.